Preventive aerobic training exerts a cardioprotective effect on rats treated with monocrotaline
نویسندگان
چکیده
منابع مشابه
Preventive effect of sildenafil on right ventricular function in rats with monocrotaline-induced pulmonary arterial hypertension
The present study aimed to evaluate the preventive effect of sildenafil treatment on pulmonary hypertension (PH) induced by monocrotaline (MCT) in rats. Fifty-four 12-week-old male Sprague-Dawley rats were injected with MCT or saline solution (MCT-injected rats: n=36; saline: n=18). Serial echocardiography and right ventricular systolic pressure (RVSP) measurements via a cardiac catheter were p...
متن کاملComparison of preventive effect of sildenafil and therapeutic effect of sildenafil treatment in rats with monocrotaline-induced pulmonary arterial hypertension
This study aimed to investigate the potential effects of sildenafil on pulmonary hypertension (PH) in the monocrotaline (MCT)-induced PH rat. Twenty-four, 12-week-old, male Sprague-Dawley rats were injected with MCT or saline solution. After injection of MCT, rats received oral sildenafil immediately (early-phase treatment group: E group), 4 weeks after injection (late-phase treatment group: L ...
متن کاملProtective Effect of Aerobic Training and Royal Jelly on Oxidative Stress in Cardiomyocytes in Obese Rats
Background and purpose: Obesity leads to a variety of metabolic changes that may contribute to abnormalities in the structure and function of the heart. The aim of this study was to investigate the effect of royal jelly and aerobic training on oxidative stress in cardiomyocytes in high-fat diet-induced obese rats. Materials and methods: In this experimental study, 45 male rats were randomly di...
متن کاملEffect of Aerobic Training and L-carnitine on MDA, GPX and Hippocampal Neurogenesis in Diabetic Rats
Objective: L-carnitine is associated with an increase in antioxidant enzymes activities and reduction in oxidative damage. The aim of this study was to evaluate the effect of aerobic training and L-carnitine cconsumption on hippocampal oxidative stress and neurogenesis factors in diabetic rats. Materials and Methods: In this experimental study, 45 male wistar rats were divided into six groups ...
متن کاملEffect of 8-Week Aerobic, Strength and Concurrent Training on Circulating Apelin in Morphine-Dependent Rats
ABSTRACT Background and Objectives: Previous studies have shown that morphine dependence leads to myocardial dysfunction. In addition, apelin plays a protective role in cardiac function. The purpose of this study was to evaluate effects of morphine dependence and three models of exercise training on serum apelin level of dependent and healthy ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Experimental Pathology
سال: 2016
ISSN: 0959-9673
DOI: 10.1111/iep.12166